Monday 13 December 2010

Banksy Toxic Rat (Toxicology Street Art)



Banksy Toxic Rat (Toxicology Street Art):
Tags: Art - Banksy - Rat - Street Art - Toxic - Toxicology
Posted by Medicalchemy
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Emergency Medicine - Endocrinology - Epidemiology - Family Medicine - Forensic Medicine - Gastroenterology - Genes - Genetics - Geriatrics - Gynecology - Haematology - Health Informatics - Hepatology - Immunology - Infection - Intensive Care - Medical Education - Medical Statistics - Metabolic Medicine - Microbiology - Nephrology - Neuroanatomy - Neuroscience - Nuclear Medicine - Nutrition - Obstetrics - Occupational Health - Oncology - Ophthalmology - Orthopaedics - Otolaryngology - Paediatrics - Palliative Care - Parasitology - Pathology - Pharmacology - Physiology - Proteomics - Psychiatry - Public Health - Radiology - Respiratory - Rehabilitation - Rheumatology - Sports Medicine - Surgery - Toxicology - Tropical Medicine - Urology - Vascular - Virology.

Nanotoxicology - Nanoparticle Exposure Diseases


Nanotoxicology - Nanoparticle Exposure Diseases:
  • Alzheimer's disease
  • Arrythmia
  • Arteriosclerosis
  • Asthma
  • Autoimmune diseases
  • Bronchitis
  • Cancer
  • Colon cancer
  • Crohn's disease
  • Death
  • Dermatitis
  • Diseases of unknown aetiology
  • Emphysema
  • Heart disease
  • Hypertension
  • Kaposi's sarcoma
  • Parkinson's disease
  • Podoconiosis
  • Thrombosis
  • Urticaria
  • Vasculitis
  • Vasoconstriction
Image: by Cristina Buzea on Wikipedia (Public Domain)
Tags: Disease - Exposure - Nanoparticle - Nanotoxicology
Posted by Medicalchemy
Medicalchemy Group: History of Medicine - Images - Mnemonics - Syndromes - Acute Medicine - Anaesthesiology - Anatomy - Anthropology - Biochemistry - Cardiology - Dentistry - Dermatology - Drug ADR - Drugs - Embryology -
Emergency Medicine - Endocrinology - Epidemiology - Family Medicine - Forensic Medicine - Gastroenterology - Genes - Genetics - Geriatrics - Gynecology - Haematology - Health Informatics - Hepatology - Immunology - Infection - Intensive Care - Medical Education - Medical Statistics - Metabolic Medicine - Microbiology - Nephrology - Neuroanatomy - Neuroscience - Nuclear Medicine - Nutrition - Obstetrics - Occupational Health - Oncology - Ophthalmology - Orthopaedics - Otolaryngology- Paediatrics - Palliative Care - Parasitology - Pathology - Pharmacology - Physiology - Proteomics - Psychiatry - Public Health - Radiology - Respiratory - Rehabilitation - Rheumatology - Sports Medicine - Surgery - Toxicology - Tropical Medicine - Urology - Vascular - Virology.

Tuesday 2 November 2010

Crack Cocaine - Main Physiological Effects (Image)



Crack Cocaine - Main Physiological Effects (Image):
  • Systemic - Increased temperature (Hyperpyrexia)
  • Pupils - Dilated pupils
  • Vestibular - Vertigo
  • Vascular - Hypertension, Vasoconstriction
  • Cardiac - Heart rate increased, Cardiac arrest risk
  • Lungs - Respiratory arrest risk
  • Neuromuscular - Muscle twitches, Tremor
Image: Crack Cocaine Main Physiological Effect
Image Source: by Mikael Häggström on Wikipedia (Public Domain)
Tags: Cardiac Arrest - Crack Cocaine - Dilated Pupils - Hypertension - Muscle Twitches - Respiratory Arrest - Tremor - Vasoconstriction - Vertigo
Posted by Medicalchemy
Medicalchemy Group: History of Medicine - Images - Mnemonics - Syndromes - Anaesthesiology - Anatomy - Biochemistry - Cardiology - Dermatology - Drugs -
Emergency Medicine - Endocrinology - Gastroenterology - Genetics - Geriatrics - Gynecology - Haematology - Hepatology - Immunology - Infection - Intensive Care - Metabolic Medicine - Microbiology - Nephrology - Neuroscience - Nutrition - Obstetrics - Oncology - Ophthalmology - Orthopaedics - Otolaryngology - Palliative Care - Parasitology - Pathology - Pharmacology - Physiology - Psychiatry - Public Health - Radiology - Respiratory - Surgery - Toxicology - Tropical Medicine - Urology - Vascular - Virology.

Cocaine-Induced Chest Pain - Differential Diagnosis


Cocaine-Induced Chest Pain - Causes & Exacerbating Factors (A to Z):
  • Acute bronchitis
  • Acute pulmonary hypertension
  • Acute systemic hypertension
  • Aortic dissection
  • Coronary artery spasm
  • Cough chest pain following inhalation
  • Haemopneumothorax
  • Myocardial ischaemia
  • Pneumomediastinum
  • Pneumopericardium
  • Pneumothorax
  • Rhabdomyolysis of chest muscles
  • Septic Embolism
Image: Cocaine 3D Model
Image Source: by Benjah-bmm27 on Wikipedia (Public Domain)
Tags: Acute Bronchitis - Aortic Dissection - Chest Pain - Cocaine - Coronary Artery Spasm - Myocardial Ischaemia - Pneumothorax - Pulmonary Hypertension - Rhabdomyolysis
Posted by Medicalchemy
Medicalchemy Group: History of Medicine - Images - Mnemonics - Syndromes - Anaesthesiology - Anatomy - Biochemistry - Cardiology - Dermatology - Drugs -
Emergency Medicine - Endocrinology - Gastroenterology - Genetics - Geriatrics - Gynecology - Haematology - Hepatology - Immunology - Infection - Intensive Care - Metabolic Medicine - Microbiology - Nephrology - Neuroscience - Nutrition - Obstetrics - Oncology - Ophthalmology - Orthopaedics - Otolaryngology - Palliative Care - Parasitology - Pathology - Pharmacology - Physiology - Psychiatry - Public Health - Radiology - Respiratory - Surgery - Toxicology - Tropical Medicine - Urology - Vascular - Virology.

Monday 25 October 2010

Digoxin Toxicity - Predisposing Factors


Digoxin Toxicity Predisposing Factors (System Related):
  • General - Old age
  • Cardiac - Myocardial ischaemia
  • Respiratory - Acute hypoxia
  • Hepatobiliary - Reduced hepatic clearance
  • Metabolic - Electrolyte disturbance, Hypokalaemia, Hypercalcaemia
  • Endocrine - Hypothyroidism
  • Renal - Reduced renal clearance, Renal insufficiency
  • Pharmacology - Drug interactions
Drug Interactions:
  • Amiodarone
  • Anticholinergic drugs
  • Captopril
  • Clarithromycin
  • Diltiazem
  • Erythromycin
  • Ibuprofen
  • Nifedipine
  • Quinidine
  • Verapamil
Image: Digoxin Molecule Wikipedia Public Domain

Wednesday 6 October 2010

Hexamethonium Man (Paton, 1954)


“He is a pink complexioned person, except when he has stood for a long time, when he may get pale and faint. His handshake is warm and dry. . . . He is thin because his appetite is modest; he never feels hunger pains and his stomach never rumbles. . . . As old age comes on he will suffer from retention of urine and impotence but frequency, precipitancy, and strangury will not worry him.”

Background:
  • This description by Paton, in 1954, summarises the effects of pharmacologic blockade of ganglionic transmission.
  • Hexamethonium blocks ganglionic nicotinic acetylcholine receptors.
  • Hexamethonium thus causes dysfunction of the efferent sympathetic & parasympathetic pathways.
Consequences of this disruption include:
  • Erectile dysfunction
  • Impaired bladder emptying
  • Orthostatic hypotension
  • Saliva production decreased
  • Sweating absence (anhidrosis)
  • Tear production decreased

Reference:
Paton WD. Transmission and block in autonomic ganglia. Pharmacol Rev 1954;6:59-67

Image: from http://ridzuanzaidi.blogspot.com/
Tags: Anhidrosis - Autonomic Nervous System - Erectile Dysfunction - Hexamethonium - Hypotension - Man - Orthostatic Hypotension - Parasympathetic Nervous System - Sympathetic Nervous System - Sweating
Posted by Medicalchemy
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Medicalchemy Toxicology Blog

This Medicalchemy (TM) blog will be about Toxicology related topics.

Tags: Blog - Toxicology
Posted by Medicalchemy
Medicalchemy Group: Images - Mnemonics - Anatomy - Cardiology - Dermatology - Drugs - Endocrinology - Gastroenterology - Genetics - Geriatrics - Gynecology-Haematology-Immunology- Infection - Metabolic Medicine - Nephrology - Neuroscience - Nutrition - Obstetrics - Oncology - Ophthalmology - Orthopaedics - Otolaryngology - Pathology-Pharmacology - Physiology- Psychiatry -Public Health - Respiratory - Surgery - Toxicology - Vascular.